http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3862159-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-26 |
| filingDate | 1973-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1975-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fef8c9cb766bafd47f19c127ed69696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45220997eac6ab1029655a1f8f47ed52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92b5dbdbb2968008aeb158620c8ee760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67b8aceaabb303120411925d8cd34569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5965fe88b1195e97c2d10a4f294843af |
| publicationDate | 1975-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3862159-A |
| titleOfInvention | 5-(haloalkyl) picolinic acid and derivatives |
| abstract | A 5-(haloalkyl)picolinic acid represented by the general formula, WHEREIN R1 represents an alkylene group having 3 to 6 carbon atoms and X represents a halogen atom, provided that the halogen atom is attached to the terminal carbon atom of the carbon chain or to the carbon atom at position 3'' in the case of a four-carbon chain, is a novel compound useful as a hypotensive agent. The said novel compound is obtained by reacting a 2-methyl-5(haloalkyl)-pyridine represented by the general formula, WHEREIN R1 and X have the same meaning as defined above, A. WITH A PEROXIDE TO FORM A 2-METHYL-5-(HALOALKYL)PYRIDINE-Noxide, converting the resulting N-oxide to a 2-hydroxymethyl-5(haloalkyl)pyridine ester by reaction with a carboxylic acid anhydride, hydrolyzing the resulting ester to a 2hydroxymethyl-5-(haloalkyl)-pyridine, and oxidizing the resulting compound with an oxidizing agent; or B. WITH BENZALDEHYDE IN THE PRESENCE OF A DEHYDRATING AGENT TO FORM A 2-STYRYL-5-(HALOALKYL)-PYRIDINE, AND OXIDIZING THE RESULTING STYRYL DERIVATIVE WITH AN OXIDIZING AGENT; OR C. WITH SELENIUM DIOXIDE TO EFFECT OXIDATION. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4556716-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5380861-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5534635-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4273779-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4036965-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4609734-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3998955-A |
| priorityDate | 1972-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.