| abstract |
Compounds having the following structural formula are disclosed: WHEREIN R1 is aryl which may be substituted or unsubstituted; R2 is alkyl, aryl, aralkyl, alkoxy, halogen, cyano, nitro, trifluoromethyl and the like. These compounds are prepared by treating a benzothiopyran-4-one 1,1-dioxide with a base and then treating the resulting anion with an appropriate arylisocyanate, or by aminolysis of the 3carboxylate ester of a benzothiopyran-4-one 1,1-dioxide. These compounds are useful as antiinflammatory agents. |