abstract |
AND -(CH2)n-Z, in which R3 and R4 are independently -H, lower alkyl or perfluoro-lower alkyl radicals, with the proviso that when R and R2 are -H, R3 is lower alkyl, Z is -H or -OH, and N IS ONE OF THE INTEGERS 3 OR 4; AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF. IN WHICH R,R1 and R2 are independently selected from the group consisting of -H and lower alkyl radicals; X is a member selected from the group consisting of -CH2OH, CHO, -CO2R5, in which R5 is -H or lower alkyl, Y is a member selected from the group consisting of Compounds of the following formula possess central nervous system depressant properties in warm blooded animals: |