abstract |
The excipient comprises hydroxy alkyl cellulose or hydroxy alkyl alkyl cellulose, wherein the average number of substituted moles of hydroxy group in glucose per anhydrous glucose unit is from 0.1 to 1.30; the average number of substituted moles of hydroxyalkyl groups per anhydrous glucose unit is from 0.05 to 1.00; and the average number of substituted moles of alkyl groups per anhydrous glucose unit is from 0 to 1.00. When the excipient is mixed with a medicament and the resultant mixture is compressed, hard, readily disintegratable tablets are produced. |