http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3843712-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
| filingDate | 1972-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1974-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_377083f53e1ac58ccb73130427737e7e |
| publicationDate | 1974-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3843712-A |
| titleOfInvention | Endo-bicyclo(3.1.0)-hexane glycol intermediates for preparing prostaglandins e1,a1,and analogs thereof |
| abstract | This invention is a group of endo-bicyclo(3.1.0)hexane glycols of the formula: IN ENDO CONFIGURATION WITH RESPECT TO THE -CH(OH)-CH(OH)-R3 moiety; wherein R1 is hydrogen, alkyl of one to 8 carbon atoms, inclusive, cycloalkyl of 3 to 10 carbon atoms, inclusive, aralkyl of 7 to 12 carbon atoms, inclusive, phenyl, phenyl substituted with one to 3 chloro or alkyl of one to 4 carbon atoms, inclusive, or ethyl substituted in the Beta -position with 3 chloro, 2 or 3 bromo, or one, 2, or 3 iodo; wherein R3 is alkyl of 2 to 8 carbon atoms, inclusive, substituted with zero to 3 fluoro, or alkyl of 2 to 8 carbon atoms, substituted with 4 or 5 fluoro on the omega and omega-minus-one carbon atoms; wherein R4 is hydrogen or alkyl of one to 4 carbon atoms, inclusive; wherein CmH2m is alkylene of 3 to 11 carbon atoms, inclusive, substituted with zero to 2 fluoro, with 3 to 7 carbon atoms, inclusive, in a chain between -CHR4- and -COOR1; and wherein * indicates attachment of the -CHR4-CmH2m-COOR1 moiety to the ring in alpha or beta configuration. These glycols are useful as intermediates for the preparation of prostaglandin E1 and analogs thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5395935-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8304019-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3997588-A |
| priorityDate | 1971-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 198.