| abstract |
1,2,3,4-TETRAHYDRO-3-AMINOMETHYLISOQUINOLINES OF THE FORMULA: 2-R1,3-(R2-N(-R3)-CH2-),6,7-DI(X-)-1,2,3,4-TETRAHYDROISO QUINOLINE WHEREIN R1 REPRESENTS HYDROGEN, A LOWER ALKYL OR AN ARALKYL RADICAL; R2 REPRESENTS HYDROGEN, A LOWER ALKYL, AN ARYL, AN ARALKYL, A SUBSTITUTED ARALKYL, A HETEROCYCLIC ALKYL OR A GUANYL RADICAL; R3 REPRESENTS HYDROGEN OR A LOWER ALKYL RADICAL; AND X REPRESENT HYDROGEN OR A LOWER ALKOXY RADICAL, AND THE PROCESS FOR PREPARING THESE COMPOUNDS STARTING WITH THE CORRESPONDING TETRAHYDROISOQUINOLINECARBOXYLATE ARE DESCRIBED. THE COMPOUNDS HAVE USEFUL ANTI-ARRHYTHMIC PROPERTIES. |