| abstract |
NOVEL 2-(2-PYRIDYL)-W-PHENYLALKYLAMINES OF THE FORMULA: (PYRID-2-YL-CH(-CH2-AM)-(CH2)N-),R-BENZENE WHEREIN AM IS AN AMINO RADICAL SELECTED FROM THE GROUP CONSISTING OF AMINO-(-NH2), DI-LOWER-ALKYLAMINO, PYRROLIDINO, PIPERIDINO AND MORPHOLINO; R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, FLUORINE, CHLORINE, BROMINE, METHOXY AND TRIFLUOROMETHYL, N IS A POSITIVE INTEGER FROM 1 TO 2 INCLUSIVE ARE PREPARED BY (A) REACTING 2-(WPHENKYLAKYLPYTIDINES WITH FORMALDEHYDE AND SECONDARY AMINES, AND (B) LITHIUM ALUMINUM HYDRIDE REDUCTION OF A-BENZYL-2-PYRIDYLACETONITRILES. THE NOVEL PRODUCTS ARE USEFUL AS ANTISECRETORY AGNETS. |