| abstract |
Water-soluble bad-tasting drugs and vitamins are put into chewable tablet form wherein the drugs and vitamins have a pleasant taste and are readily available upon ingestion. A water solution or water-alcohol solution of the bad-tasting substance is absorbed into rice endosperm using about enough solution for complete hydration or slightly less, followed by drying. Precooked rice endosperm can also be used. The drugs include phenothiazine tranquilizers and barbiturates and the vitamins include thiamin, niacinamide and pyridoxine. The water-soluble substance may constitute up to 60 percent of the finished product, with the rice endosperms, which may be previously comminuted, making up the balance. The pleasant tasting chewable tablets contain the bad tasting substance with the bad taste masked, conventional chewable tablet base constituents for the tableting of the rice endosperm-drug particles being combined with the treated rice endosperms. |