| abstract |
WHEN AN ALDEHYDE IS REACTED WITH CARBON MONOXIDE AND THE AMIDE OF A CARBOXYLIC ACID IN THE PRESENCE OF A CARBONYLATION CATALYST, THERE IS OBATINED THE N-ACYL DERIVATIVE OF AN A-AMINO ACID HAVING ONE MORE CARBON ATOM THAN THE ALDEHYDE USED, THE ACYL GROUP CORRESPONDING TO THAT OF THE AMIDE. THE REACTANTS MAY BE FORMED N SITU. AMINO ACIDS MAY BE PRODUCES BY HYDROLYZING THE N-ACYL-AAMINO ACID. |