| abstract |
PROCESS FOR PRODUCING L-GLUTAMIC ACID WHICH COMPRISES CULTURING A MICROORGANISM CAPABLE OF PRODUCING L-GLUTAMIC ACID UNDER AEROBIC CONDITIONS IN AN AQUEOUS NUTRIENT MEDIUM CONTAINING AT LEAST ONE HYDROCARBON AS THE MAIN CARBON SOURCE AND AN ANTIBIOTIC AND A DISPERSING AGENT FOR SAID HYDROCARBON. EXEMPLARY ANTIBIOTICS INCLUDE PENICILLIN, BACITRACIN, CYCLOSERINE, KANAMYCIN, STREPTOMYCLIN, SPRIAMYCIN, CEFALOTIN, CEPHALORIDINE AND NOVOBIOCIN. EXEMPLARY DISPERSING AGENTS INCLUDE ANONIC, CATIONIC AND NONIONIC SUBSTANCES AND HIGHER FATTY ACIDS AND ORGANIC ESTERS. THE COMBINATION OF AN ANTIBIOTIC AND A DISPERSING AGENT IN THE MEDIUM GIVES A SYNERGISTIC EFFECT, RESULTING IN A REMARKABLE ACCELERATION IN THE PRODUCTION OF L-GLUTAMIC ACID. |