| abstract |
UNSYMMETRICAL TERTIARY ORGANOPHOSPHINES SELECTED FROM (A) COMPOUNDS OF THE FORMULA 1: Q-P(-Q'')-Q" WHEREIN Q IS -(CH2)N-CH(-R5)-C(-Z)(-R4)-R3 AND WQ'' IS -CH2-CH(-R6)-C(-Z)(-R7)-R8 AND Q'''' IS Q, Q'', ALKYL, CYCLOALKYL, ALKENYL, CYCLOALKENYL, CYANOALKYL, CARBOXYALKYL OR CARBAMIDOALKYL, AND WHERE Z IS-OH OR -NR1R2 WHERE R2 INDEPENDENTLY ARE HYDROGEN OR ALKYL (C1-C4), R2 MAY BE ACETYL, CARBAMYL OR GUANYL WHEN R1 IS HYDROGEN, OR R1 TOGETHER WITH R2 AAND THE NITROGEN ATOM OF-NR1R2 FORM A MORPHOLINYL OR PIPERIDINYL RING, PROVIDED Z IN Q AND Q'' ARE DIFFERENT, R3 THROUGH R8 INDEPENDENTLY ARE HYDROGEN OR ALKYL (C1-C4), AND N IS 0-3, AND (B) ACID SALTS OF SAID COMPOUNDS SUCH AS THE HYDROCHLORIDES. THE COMPOUNDS AND SALTS ARE DEPILATORY AGENTS. |