abstract |
The present invention relates to new, pharmacologically valuable piperazine derivatives of the general formula WHEREIN A means an alkyl or hydroxyalkyl radical having from one to four carbon atoms in the alkyl moieties, a benzhydryl or phenyl radical or one of the groups -COOR or R representing alkyl having from one to four carbon atoms and the benzene rings B and/or C may be substituted by halogen AND TO THE PRODUCTION OF SUCH DERIVATIVES BY REACTING A COMPOUND OF THE GENERAL FORMULA WHEREIN D stands for ONa, OK, OH, Cl or Br with a piperazine compound of the general formula WHEREIN A has the meaning given above, or by reacting, at a molar ratio of 2:1, a compound of the general formula WHEREIN D means ONa, OK, OH, Cl or Br with piperazine. |