| abstract |
(4,3-A)(1,4)BENZODIAZEPINE 1-R,4-R1,6-(R2,R3-PHENYL),R4,R5-4H-S-TRIAZOLO A MULTISTEP PROCESS FOR THE PRODUCTION OF TRIAZOLOBENZODIAZEPINES OF THE FORMULA 1: WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND ALKYL OF 1 TO 3 CARBON ATOMS, INCLUSIVE; WHEREIN R1 IS HYDROGEN OR ALKYL DEFINED AS ABOVE; AND WHEREIN R2, R3, R4, AND R5 ARE SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ALKYL DEFINED AS ABOVE, FLUORINE, CHLORINE, BROMINE, NITRO, CYANO, TRIFLUOROMETHYL, ALKOXY OF 1 TO 3 CARBON ATOMS, INCLUSIVE, AMINO, ALKANOYLAMINO IN WHICH THE ALKANOYL GROUP IS OF 1 TO 3 CARBON ATOMS, INCLUSIVE, ALKYLTHIO, IN WHICH THE ALKYL GROUP IS DEFINED AS ABOVE, ALKYLSULFINYL, IN WHICH THE ALKHL GROUP IS DEFINED AS ABOVE, AND DIALKYLAMINO, IN WHICH THE ALKYL GROUP IS DEFINED AS ABOVE, AND FOR SOME OF INTERMEDIATES IS CLAIMED. THE FINAL COMPOUNDS AND INTERMEDIATES ARE TRANSQUILIZERS AND SEDATIVES AND ARE USEFUL IN MAMMALS, INCLUDING MAN AND BIRDS. |