abstract |
Anthelmintically useful mono- or di-isothiocyano substituted diphenyl ethers, sulfides, sulfoxides and sulfones, the molecule of which must contain either a dialkylamino, or, preferably, one nitro group and which optionally are further substituted by alkyl, alkoxy or chlorine are described; such compounds when applied in anthelmintically effective dosage, are unexpectedly well tolerated by the organism of warm-blooded animals, in contrast to other structurally closely related isothiocyano diphenyl ethers, which are too toxic to be satisfactory anthelmintic agents. |