| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b4b60cba656bd8dca638e056299db88 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-10 |
| filingDate |
1970-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1972-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b69645d88e0d4afc7f87591436b07708
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2fa2fa84f2d0fea9dbeacb406d3c0a8 |
| publicationDate |
1972-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-3691198-A |
| titleOfInvention |
Synthesis of 1-substituted-3-halopyrrolidines |
| abstract |
A method of preparing 1-substituted-3-halopyrrolidines, particularly a method of preparing said pyrrolidines by reacting a 1-substituted- Delta 3-pyrroline with a concentrated hydrogen halide aqueous solution at a temperature greater than 100*C. In a preferred embodiment, a supersaturated hydrobromic acid solution is utilized, i.e., one containing about 60 percent hydrogen bromide. The 1-substituted- Delta 3-pyrroline reactant is preferably made by reaction of a cis-1,4-dihalobutene-2 with a primary amine whereupon cyclization takes place. Said 1substituted-3-halopyrrolidines are intermediates useful in making anti-cholinergics and like materials. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101182304-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6479668-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6130338-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0985664-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102675179-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0985664-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7253182-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003220400-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4254135-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6307060-B1 |
| priorityDate |
1970-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |