http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3681394-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-30 |
| filingDate | 1970-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1972-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07bb8ebbe79189baaf0fa6d959d17fd6 |
| publicationDate | 1972-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3681394-A |
| titleOfInvention | Glyceryl-n-(substituted phenyl) anthranilates |
| abstract | The invention relates to glyceryl esters of N-X,Y,Z-phenyl (anthranilic acids), to their use as analgesic anti-inflammatory agents, and to the intermediates useful in the preparation thereof. Illustrative of the preparation of those compounds is the formation of glyceryl-N-(3-trifluoromethylphenyl) anthranilate, as follows: Reflux a mixture containing N-(3trifluoromethylphenyl) anthranilic acid, chloroacetonitrile in the presence of triethylamine to produce cyanomethyl-N-(3trifluoromethylphenyl) anthranilate which, by heating with 2,2dimethyl-1,3-dioxolane-4-methanol in the presence of anhydrous potassium carbonate, produces Beta - gamma isopropylidenedioxypropyl anthranilate. Hydrolysis of the Beta gamma -isopropylidenedioxypropyl-N-(3-trifluoromethylphenyl) anthranilate with 75 percent acetic acid for 35 minutes yields glyceryl N-(3-trifluoromethylphenyl) anthranilate. Alternate methods for the preparation of the glyceryl esters of N-(X,Y,Zphenyl) anthranilic acids are also described. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4166128-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4058550-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4272529-A |
| priorityDate | 1970-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.