http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3657229-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5173a7d063a9f70ca7b5e86fc23863 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-00 |
| filingDate | 1968-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1972-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_853506b45de3d56e44eb379b5d222913 |
| publicationDate | 1972-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3657229-A |
| titleOfInvention | 1 3-diaza-2 3-cycloalkene derivatives |
| abstract | 2-(A-(LOWER-ALKOXY) BENZYL) -2-IMIDZOLINES,-1,4,5,6TETRAHYDROPYRIMIDINES AND -4,5,6,7-TETRAHYDRO-1H-1,3-DIAZEPINES, HAVING PHARMACOLOGICAL PROPERTIES, E.G., HYPOGLYCEMIC, DIURETIC, ANTI-INFLAMMATORY, ARE PREPARED BY HEATING A 2-(LOWER-ALKOXY)-2-PHENYLALKANENITRILE WITH AN ALKANEDIAMINE, WHEREIN 2,3 OR 4 CARBON ATOMS, RESPECTIVELY INTERVENE BETWEEN THE TWO AMINO GROUPS, IN THE PRESENCE OF A CATALYTIC AMOUNT OF CARBON DISULFIDE OR HYDROGEN SULFIDE. THE INTERMEDIATE 2-(LOWER-ALKOXY)-2PHENYLALKANENITRILES ARE PREPARED PREFERABLY BY FIRST REACTING A BENZALDEHYDE WITH A TRI-(LOWER-ALKYL) ORTHOFORMATE TO FORM THE ALDEHYDE DI-(LOWER-ALKYL) ACETAL, REACTING THE LATTER WITH AN ACYL HALIDE TO FORM THE CORRESPONDING AHALOBENZYL LOWER-ALKYL ETHER AND REACTING SAID ETHER WITH AN ALKALI CYANIDE TO YIELD SAID INTERMEDIATE NITRILE. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3869456-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3996207-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4260626-A |
| priorityDate | 1968-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 356.