http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3642983-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23736bb38ce953aba7f4a3907ed3bc49 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-407 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-407 |
| filingDate | 1969-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1972-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f56759aa9e119012874ec5cee26d7241 |
| publicationDate | 1972-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3642983-A |
| titleOfInvention | Method of preparing injectable liver extracts |
| abstract | A METHOD FOR PREPARING AN INJECTABLE LIVER EXTRACT COMPRISING THE FOLLOWING STEPS: (A) WHEREIN GROUND LIVER IS FIRST DIGESTED AND DISPERSED IN WATER ACIDIFIED BY SULFURIC ACID HAVING A PH IN THE RANGE OF FROM 5.3 TO 5.8; (B) WHEREUPON THE LIQUID PHASE IS CONCENTRATED AND DEPRIVED OF ITS PROTEIC FRACTION FOR ORAL ADMINISTRATION BY PRECIPATION WITH AN ORGANIC SOLVENT, THE DISSOLVED MATTER BEING RECOVERED FOR PREPARING THEREFROM, AN INJECTABLE AQUEOUS SOLUTION; (C) SAID METHOD BEING CHARACTERIZED IN THAT THE DIGESTION STEP IS CARRIED OUT IN A TEMPERATURE RANGE OF FROM 45*C. TO 50*C. FOR A PERIOD OF FROM 5 TO 8 HOURS, FOLLOWED BY FILTERING SAID DISPERSION, WHEREAFTER THE LIQUID PHASE IS CONCENTRATED ING THE VACUO AT A TEMPERATURE NOT EXCEEDING 35*C., TO A DRY MATTER CONTENT OF FROM 13% TO 18% BY EIGHT, AND SUBJECTED TO DEPROTEINIZATION BY TREATMENT WITH ACETONE AT A TEMPERATURE OF 15*C. TO 25*C., THEREAFTER SEPARATING SAID PROTEIC FRACTION FOR ORAL ADMINSTRATION THROUGH FILTRATION, TEH RESULRING AQUEOUS-ACETONIC SOLUTION BEING DEPRIVED OF ACETONE BY CONCENTRATION THROUGH EVAPORATION AT A TEMPERATURE NOT EXCEEDING 32*C. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5679580-A |
| priorityDate | 1968-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.