http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3641005-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate | 1970-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1972-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80da6b00b6fc55daed72c5242b7e312a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2fc3fc3a8335f9989a382430070edb9 |
| publicationDate | 1972-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3641005-A |
| titleOfInvention | Process for the preparation of delta**4-6 6-difluoro - 320 - diketo - 17alp ha21-dihydr-oxypregnenes |
| abstract | TITLE COMPOUNDS ARE PREPARED FROM $5-3-ALKANOYL17A,20; 20,21-BISMETHYLENEDIOXYPREGNENES BY A PROCESS INVOLVING THE ADDITION OF NOF; HYDROLYSIS OF THE RESULTING 5A-FLUORO-6-NITRIMINOSTEROID TO THE 5A-FLUORO-6-KETOSTEROID; HYDROLYSIS OF THE 3-ALKANOYL AND BISMETHYLENEDIOXY GROUPS WITH 48% HYDROFLUORIC ACID; ACETYLATION OF THE 3-, 17A-, AND 21-HYDROXYLS, FLUORINATION WITH SULFUR TETRAFLUORIDE TO THE CORRESPONDING 5A,6,6-TRIFLUOROSTEROID; HYDROLYSIS OF ALL ACETYL GROUPS; RE-FORMATION OF THE 17A,20; 20,21-BISMETHYLENEDIOXY GROUP; OXIDATION OF THE 3-HYDROXYL TO THE 3-KETONE; DEHYDROFLOURINATION IN THE C4-C5 POSITIONS; AND REMOVAL OF THE BISMETHYLENEDIOXY GROUP. AN ALTERNATIVE ROUTE ALSO IS PROPOSED. TITLE STEROIDS HAVING AN OXYGENATED FUNCTION IN THE 11B-POSITION ARE USEFURL ANTIINFLAMMATORY AND GLUCOCORTICAL AGENTS. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0340037-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0340037-A2 |
| priorityDate | 1970-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.