| abstract |
PYRROLINE DERIVATIVES OF THE FORMULA: WHEREIN R AND R'' ARE THE SAME OR DIFFERENT AND EACH REPRESENTS A HYDROGEN ATOM OR AN ALKYL GROUP CONTAINING 1 TO 5 CARBON ATOMS (PREFERABLY METHYL), AND THE BENZENE RING IS UNSUBSTITUTED OR CARRIES ONE OR MORE SUBSITUENTS SELECTED FORM HALOGEN ATOMS, ALKYL AND ALKOXY GROUPS CONTAINING 1 TO 5 CARBON ATOMS, AND GYDROXY, NITRO AND AMINO GROUPS, AND THEIR ACID ADDITION SALS, POSSESS PHARMACODYNAMIC PROPERTIES. THEY ACT ON THE CENTRAL NERVOUS SYSTEM, AND ARE ESPECIALLY USEFUL AS ANTI-DEPRESSANTS; FURTHERMORE, THEY SHOW A HYPERTENSIVE EFFECT. 2-(R-N(-R'')-),4-PHENYL-1-PYRROLINE |