http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3621062-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5173a7d063a9f70ca7b5e86fc23863 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-83 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C46-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-112 |
| filingDate | 1969-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1971-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ab22d4bf6045aa5058cd6b7253bb3a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02346d87864962766f935728bebfe50c |
| publicationDate | 1971-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3621062-A |
| titleOfInvention | 2-(8-cyclohexyloctanoyl or 7-cyclohexylheptanoyl)-1-naphthol |
| abstract | Intermediates for the preparation of 2-hydroxy-3-(8cyclohexyloctyl)-1,4-naphthoquinone and 2-hydroxy-3-(7cyclohexylheptyl)-1,4-naphthoquinone, potent antimalarial agents, are prepared as follows: reacting 8-cyclohexyloctanoic acid or 7cyclohexylheptanoic acid with 1-naphthol to form 2-(8cyclohexyloctanoyl or 7-cyclohexylheptanoyl)-1-naphthol; reducing the 2-acyl-1-naphthol to form 2-(8-cyclohexyloctyl or 7cyclohexylheptyl)-1-naphthol; oxidizing 2-(8-cyclohexyloctyl or 7-cyclohexylheptyl)-1-Napthol to form 2-(8-cyclohexyloctyl or 7cyclohexylheptyl)-1,4-naphthoquinone; reacting the latter with a peroxide under alkaline conditions to form 2-(8-cyclohexyloctyl or 7-cyclohexylheptyl)-1,4-naphthoquinone-2,3-oxide; and, hydrolyzing the 2,3-oxide under acidic conditions to yield 2hydroxy-3-(8-cyclohexyloctyl or 7-cyclohexylheptyl)-1,4naphthoquinone. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008125411-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7371778-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6906205-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6486199-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004186168-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008125441-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005256185-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8067620-B2 |
| priorityDate | 1966-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.