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filingDate 1969-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1971-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1971-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-3616258-A
titleOfInvention Diagnostic product and process for the detection of niacin production by mycobacteria
abstract A diagnostic product for the detection of niacin produced by ''''human'''' Mycobacterium tuberculosis is prepared by impregnating a plurality of individual but separated zones on a paper strip with a series of reagents which include (1) an alkali metal salt of p-aminobenzoic acid; (2) sodium or potassium thiocyanate; (3) a crystalline acid such as citric, oxalic or malonic; and (4) chloramine-T. The desired diagnostic test employing the impregnated paper strip is performed by bringing the strip into contact and in a sealed test tube with an extract of the culture to be tested. If niacin is present the reaction of the several reagents with the niacin leads to color formation as a positive test for the presence of niacin.
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