| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79751aeaa9923745648e5ae7d9c35782 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-568
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05B3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-568
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-02 |
| filingDate |
1968-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1971-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30c6e9830cb1c9f2796e6decfa8a11ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a01ab7599f20b0fe5d8d9c88d1645a65 |
| publicationDate |
1971-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-3584016-A |
| titleOfInvention |
18-methylene-steroids of the pregnane series |
| abstract |
18-METHYLENE-STEROIDS OF THE PREGNANE AND ANDROSTANE SERIES AND THE CORRESPONDING 19-NOR-DERIVATIVES ARE NEW AND PHARMACOLOGICALLY ACTIVE COMPOUND USEFUL AS GESTAGENIC, OVULATION INHIBITING AND ANABOLIC-ANDROGENIC AGENTS. NEW METHODS FOR THE PREPARATION OF 18-METHYLENESTEROIDS IN GENERAL ARE BASED ON THE CONVERSION OF N-OXIDES OF TERTIARY 18-AMINOMETHYL STEROIDS INTO 18METHYLENE-STEROIDS AT ELEVATED TEMPERATURE AND ON THE REACTION OF 18-OXO-STEROIDS ACCORDING TO WITTIG''S METHOD WITH METHYLENE-PHOSPHORANES A SPECIAL METHOD FOR THE PREPARATION OF THE 18-METHYLENE-COMPOUNDS OF THE PREGNANE SERIES CONSISTS IN THE SPLITTING OF 18-SULFONIC ACID ESTERS OF 18,20-DIHYDROXY - 18A,20 - CYCLOHOMOPREGNANE COMPOUNDS WITH STRONG BASES. OTHER SPECIAL PROCESSES ARE DESCRIBED STARTING FROM COMPOUNDS HAVING THE 18-METHYLENE GROUP AND IN WHICH OTHER FUNCTIONS IN THE STEROID MOLECULE ARE MODIFIED ACCORDING TO KNOWN METHODS. |
| priorityDate |
1967-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |