http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3553226-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba090c867801ab7bccb082f1b694ad25 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-112 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-52 |
| filingDate | 1968-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1971-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a49b889e51b112bd8faea4616d8b3f26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67496182f3bf43b91f0e72890d679516 |
| publicationDate | 1971-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3553226-A |
| titleOfInvention | 1-(2-benzoylcyclopropylmethyl)-4-phenyl-1,2,5,6- tetrahydropyridines |
| abstract | 1 - (2- BENZOYLCYCLOPROPYLMETHYL) - 4 - PHENYL-1,2,5,6TETRAHYDROPYRIDINES AND RELATED 4-PHENYLPIPERAZINES IN WHICH THE BENZOYL GROUP AND/OR THE PHENYL MOIETY MAY BE SUBSTITUTED BY CHLORO, BROMO, FLUORO, TRIFLUOROMETHYL, METHYL OR METHOXY, AS WELL AS THE ETHYLENE KETALS THEREOF, HAVE TRANQUILIZING ACTIVITY. THE COMPOUNDS ARE GENERALLY PREPARED FROM A 2-BENZOYLCYCLOPROPANECARBOXYLIC ACID VIA REACTION OF THE TRIETHYLAMINE SALT WITH ETHYL CHLOROFORMATE TO GIVE THE MIXED ANHYDRIDE WHICH IS CONDENSED WITH A 4-PHENYL-4-PEPERIDONOL OR 1-PHENYLPIPERAZINE TO GIVE A CORRESPONDING AMIDE. THE ETHYLENE KETAL OF THE AMIDE IS REDUCED TO THE CYCOPROPYLMETHYL DERIVATIVE WHICH IS HYDROLYZED WITH ACID TO FREE KETONE PRODUCT. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4227015-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3976673-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2168946-A1 |
| priorityDate | 1968-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.