| abstract |
An analgesic preparation for application to the oral mucosa (including the gingival and lip surfaces) comprises an aqueous or hydroalcoholic gel and a water-soluble salicylate compound dissolved in said gel, said preparation having a pH of from 4 to 7. Generally, the preparation has a salicylate ion concentration of 2 to 10% by weight. Salicylate compounds specified are choline, potassium, sodium, calcium and morpholine salicylates. The gelling agent for the preparation may be methyl cellulose, methyl ethyl cellulose, polyoxythylene glycol, polyvinyl pyrrolidone, dextran, gum guar, algin gum, gum acacia or gum tragacanth. Optional ingredients include antiseptics, e.g. cetyldimethylbenzylammonium chloride, antibiotics, e.g. penicillin and penicillin salts, tyrothricin, tetracycline and neomycin, and flavouring and sweetening agents, e.g. cyclohexylsulphamic acid. |