| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C14-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C14-081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C14-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C14-5853
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-553 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C14-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C14-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C14-18 |
| filingDate |
2022-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2a47bf6873d2bed5c2a549f1a1006f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b44e939b8cbad0667a39faa8f4e25b70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95c44abcd42b4f15e6a93c6eeb8441de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa8e34d757f7a76289bf91915ee3b742
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65759b96e1032b82ab0f85d168bfb16d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3655c4ac96ee61100130e430f9851d1 |
| publicationDate |
2022-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022397533-A1 |
| titleOfInvention |
Aluminum thin film microarray chip substrates for biosensing via surface plasmon resonance spectroscopy and imaging |
| abstract |
A thin aluminum film substrate and microarrays thereof including a substrate and a thin film of aluminum deposited on the substrate for surface plasmon resonance analysis. Methods of forming the thin aluminum film substrate and microarrays including providing a substrate, using electron-beam physical vapor deposition (EBPVD) to deposit a thin film of Al on a surface of the substrate. Also disclosed are methods of detecting an analyte, wherein a functionalized surface of the thin aluminum film includes a biomolecule and the methods include applying a sample including the analyte to the thin aluminum film substrate, and using surface plasmon resonance (SPR) spectroscopy to detect molecular interactions between the biomolecule and the analyte at a surface of the thin aluminum film substrate. In some examples, an unmodified Al film with an Al2O3 layer is effective in enriching phosphorylated peptides. In some examples, a coating of an ionic polymer is used to analyze charged-based interactions of biomolecules. |
| priorityDate |
2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |