| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdc2787a32cce910a72605c3d3b8133c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_867345a3eef20e9a7bf53202dc069858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1cf697231ab03a1634b44cd25248cf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c30b9769c357df9960fa630c492ea4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91d5ee4a7966945cd5882ab4fce13334 |
| publicationDate |
2022-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022396576-A1 |
| titleOfInvention |
Process for preparing an activin receptor-like kinase inhibitor |
| abstract |
The present disclosure provides a method of preparing a compound represented by formula (I). The method comprises reacting in a reaction mixture a first starting material represented by formula (II) and a second starting material represented by formula (III) under Negishi conditions: to form the compound of formula (I). R is an amine protecting group; Y is Cl, Br or I; and Z is triflate, Cl, Br or I. |
| priorityDate |
2019-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |