| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e96c76609bbd9fbc2a5ee5e4b9f7e164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_810275606b0f9be3d7995f66e47baa89 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2835
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2817
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-446
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L67-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L67-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 |
| filingDate |
2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0b513a1033e6ab0a7b84d34919d64a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fa5e5581be6fa04f95c9a64ef1812ca |
| publicationDate |
2022-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022395610-A1 |
| titleOfInvention |
Bone regeneration material having a cotton-wool like structure formed of a plurality of electrospun fibers |
| abstract |
A bone regeneration material has a cotton-wool like structure formed of a plurality of electrospun fibers that contain bound BMP-2 through β-TCP binding peptide. The electrospun biodegradable fiber contains 25-65 vol % of β-TCP particles distributed in the fiber such that a portion of the β-TCP particles is exposed on a surface of the electrospun fiber and the remaining portion of the β-TCP particles is buried in the fiber. β-TCP binding peptides that are fused with BMP-2 are bound to the β-TCP particles so that BMP-2 is tethered to β-TCP particles on the surface of the fibers. Upon implantation of the bone regeneration material in a bone defect site of a human body, BMP-2 that are tethered to β-TCP particles on the surface of the bone regeneration material promotes proliferation and differentiation of cells at the bone defect site. |
| priorityDate |
2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |