http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022389407-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f4ef39131394f4ff77012c1366b83ea |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3098c83589757c00ac2342f14b8ff87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_227265b3034b9828ade75c9a447d543e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42ea21e10a59a1562b956b12803fa76f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c55c645d8570c6c10e5ae9ca4d5c6f6 |
| publicationDate | 2022-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022389407-A1 |
| titleOfInvention | Method for aptamer selection and identification |
| abstract | The present disclosure provides a novel approach, recomSELEX, that highly integrate mutually supportive recombination and computational methods for aptamer selection and identification. The recomSELEX approach comprises a recombinatorial SELEX platform for aptamer screening that exponentially increases the sequence space that is explored by incorporation of a DNA shuffling step that allows recombination between aptamers. Subsequently, the recombinatorial SELEX platform can also be employed to develop new and optimize already existing aptamers. The recomSELEX further comprises a computational SELEX platform with a constrained genetic algorithm (GA) to identify potential aptamers that are stable and have the desired specificity and affinity of a target. |
| priorityDate | 2021-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.