| abstract |
In accordance with embodiments of this disclosure, a computational simulation platform for assessing impact of coronary artery bypass grafting comprises a computer-implemented method that includes: generating patient-specific three-dimensional (3D) reconstructions of path lines for a patient's heart, ascending aorta, aortic arch, descending thoracic aorta, great vessels, coronary arteries and their major branches based on noninvasive imaging; performing virtual CABG by modifying the patient-specific 3D reconstructions to computationally add path lines for one or more bypass grafts; performing post-virtual CABG computational fluid dynamic (CFD) studies under computational resting and stress conditions; and assessing hemodynamic impact of virtual CABG on the resting and hyperemic flow of diseased native coronary arteries and virtual bypass grafts. |