| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da6012a6809db78e155927b5ba9b955d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19bc7ba64f8487104bf8e6dd73b6c422 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-0104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2021-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd537964e3061d6efc837df4f567c1b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75064713ba9ab4b18c9b6f62bcc09bc0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df77a88d847ab25f8d6214d946ce3e9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f42744ede2b3c5b0d7be30844d07654c |
| publicationDate |
2022-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022372473-A1 |
| titleOfInvention |
Antisense compounds and uses thereof |
| abstract |
The present invention provides compounds comprising oligonucleotides complementary to a pyruvate kinase M transcript. Certain such compounds are useful for hybridizing to a pyruvate kinase M transcript, including but not limited to a pyruvate kinase M transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the pyruvate kinase M transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with cancer. |
| priorityDate |
2012-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |