| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e345c8d1967f7a3c35bb4fb8be90615 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-204
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2535-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-191 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1065 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2020-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49cd7ede9ba93116205998473669c3f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0271eaebcd89a4fbefb5b39b033ab45b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5e7b0f1760dda86b8fbfacd1496db0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2128083556fa220fc73f9bef8f201993
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3be70162ebe1bebcf247b3ccf663517d |
| publicationDate |
2022-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022364080-A1 |
| titleOfInvention |
Methods for dna library generation to facilitate the detection and reporting of low frequency variants |
| abstract |
Methods are disclosed for adding adapters to fragmented nucleic acids for next generation sequencing, including providing numerical codes based on variable adapter molecular barcode lengths on both sides of the fragmented nucleic acids and identifying reads from the same fragment based on both barcodes. The methods and products allow for the amplification of the fragmented nucleic acids when there is a low yield of isolated fragmented nucleic acids and also for efficient and reliable detection of low-frequency mutations including in subpopulations of cells within a subject. |
| priorityDate |
2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |