| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_225f935296a460e57d48e02d72306289 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-482
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21073 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 |
| filingDate |
2020-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01bcf66b02b372eabe9c770a141444d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a76a1f4484cf1fede6db7153e2e08357
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b28764e57deb4b4be2ca9c3f3872505f |
| publicationDate |
2022-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022362355-A1 |
| titleOfInvention |
Thrombolytic Agents for Intravascular Clots |
| abstract |
Provided is a thrombolytic agent for ‘intravascular thrombus’, and more particularly, to a thrombolytic agent having a thrombo-recognition domain and a thrombolytic domain. It also relates to a polypeptide for thrombolysis of an intravascular thrombus, a gene for that polypeptide, and a pharmaceutical composition containing the same. The polypeptide that recognizes ‘intravascular thrombus’ and dissolves thrombus of the present invention is characterized in that it consists of a thrombolytic domain comprising the amino acid sequence set forth in SEQ ID NO: 1 or SEQ ID NO: 2 and a thrombo-recognition domain comprising the amino acid sequence set forth in SEQ ID NO: 3 or SEQ ID NO: 4. According to the present invention, the polypeptide for dissolving thrombus by recognizing ‘intravascular thrombus’ dissolves thrombus in the blood of a mammal without serious bleeding side effects has a preventive and therapeutic effect on thrombosis, thus preventing thrombosis and related diseases. |
| priorityDate |
2019-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |