http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022347182-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
| filingDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_040771c8bebd59ed8dd7fe4b986ea5d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9542f31cbfa21107b368bf4b5bd4dc7 |
| publicationDate | 2022-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022347182-A1 |
| titleOfInvention | Methods and compositions for the treatment of osteoarthritis |
| abstract | Provided herein are methods and compositions for reducing inflammation and/or treating osteoarthritis in a patient in need thereof. The methods include administering to the patient an inhibitor of an inflammation amplifying (Inf-A) population of chondrocytes and an activator of an inflammation dampening (Inf-D) population of chondrocytes. The methods include exposing the osteoarthritic chondrocytes to a composition including an effective amount of an ALK5 inhibitor, a JNK kinase inhibitor, a TNFR II receptor inhibitor, and/or IL1R1 receptor inhibitor and an effective amount of a CD24 activator. |
| priorityDate | 2019-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 534.