http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022323461-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d72f446413dd929ff85a4324fa4d535c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-155 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 |
| filingDate | 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6843ec8ae5540a46b08a8f0b8115f94a |
| publicationDate | 2022-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022323461-A1 |
| titleOfInvention | Method of treating late-onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency by individually tailored glucocorticoid regimen |
| abstract | A method of treating late-onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency by individually tailored glucocorticoid regimen is provided. The method can be practically used to treat adult humans who suffer from symptoms of late-onset 21-hydroxylase deficiency caused by the mutation of the CYP21A2 gene. The method consists of daily intake of two glucocorticoids: dexamethasone in evenings and hydrocortisone in the mornings, in doses specially selected for each patient based on the analysis and monitoring of 17α-hydroxyprogesterone, progesterone, sex hormone-binding globulin, adre-nocorticotropic hormone, fasting glucose, hemoglobin A1C, C-Peptide, the Parathyroid Hormone intact, blood pressure, body weight. During glucocorticoid intake, in order to counterbalance ad-verse reactions, the patient should also take supplements of potassium, calcium, vitamin D and vitamin K. |
| priorityDate | 2021-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 346.