http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022308001-A1

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filingDate 2022-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b66b00d9e65fc05aa96c77eb153faea0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45dd373d4fbe21c1b8f107e3ad9664d
publicationDate 2022-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022308001-A1
titleOfInvention Apparatus and method for single cell discrimination
abstract A method includes providing a fluid to a structure including an aperture, applying a voltage signal to a circuit that includes the fluid, applying a substantially periodic pressure signal to the fluid, detecting a current signal in the circuit as an analyte passes through the aperture in response to the substantially periodic pressure signal, and processing the current signal and the substantially periodic pressure signal to determine a switch time and a release time for the analyte. An apparatus includes a structure including an aperture to receive a fluid, a voltage source to provide a voltage signal to an electronic circuit having a path that includes the aperture, a pressure signal generator to provide a substantially periodic pressure signal to the fluid, and a system to process the periodic pressure signal and a current signal induced in the electronic circuit.
priorityDate 2021-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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