abstract |
Disclosed are compounds of Formula A, or a salt thereof: Wherein “A 1 ”, R 1 , R 2 , R 3 , R 6 , and R 7 are as defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating cough, itch and neuropathic pain disorders using the same. |