| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217b44cab2d93ab10ddf7ec199cd4f11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50704983349712c58e801666db2df344
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_970611f08951497db8cd039872a72eb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b3b3a2cc24113bd544f8595dd3578ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49832b944a965b052a27a3c6b4715e3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcbc09a69b4ab1c3bbdcd956a79cb9ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94f3b96a9071954705cafc13e330ac28 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55588 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-116 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 |
| filingDate |
2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c19f3d86f2fcd9c44d65ef8539008024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a4c028eec5db634cda674b828c4d962
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e37dbb983d1f5b57408a8058662775d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e7bb911b9e71fc31c88915ac04218b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69180c9f67a3280cc89d6b1cce06ceb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56ed273b42c0dff617b1d9fbe6693daf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae31f62a40c684bb6cda6694c8072760 |
| publicationDate |
2022-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022296695-A1 |
| titleOfInvention |
Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| abstract |
The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide from an S. pneumoniae serotype conjugated to a carrier protein, wherein the serotypes of S. pneumoniae are as defined herein. In some embodiments, at least one of the polysaccharide protein conjugates is formed by a conjugation reaction comprising an aprotic solvent. In further embodiments, each of the polysaccharide protein conjugates is formed by a conjugation reaction comprising an aprotic solvent. Also provided are methods for inducing a protective immune response in a human patient comprising administering the multivalent immunogenic compositions of the invention to the patient. The multivalent immunogenic compositions are useful for providing protection against S. pneumoniae infection and/or pneumococcal diseases caused by S. pneumoniae. The compositions of the invention are also useful as part of treatment regimes that provide complementary protection for patients that have been vaccinated with a multivalent vaccine indicated for the prevention of pneumococcal disease. |
| priorityDate |
2018-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |