| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd6979b05020fb18f7526390988a8650 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1384
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0667
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0653
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-35 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate |
2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a80150b03f8a6f17c0c81c1943396b08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bf9b89b5468493d2b4ae7cf7da50f15 |
| publicationDate |
2022-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022296649-A1 |
| titleOfInvention |
Method for preparing matrilin-3 pretreated stem cell speroids, and composition, derived therefrom, for preventing or treating cartilage diseases |
| abstract |
Provided are a method of preparing a spheroid of stem cells and a composition including the spheroid prepared by the method, the method including: culturing stem cells in a medium supplemented with matrilin-3 protein; and performing 3D cell culture on the cultured stem cells in the medium. The composition disclosed herein has effects of preventing or treating cartilage disease. In detail, the composition may be able to further promote cartilage differentiation of adult stem cells and reduce dedifferentiation and hypertrophy that may occur during cartilage regeneration, thereby providing a more effective cartilage tissue regeneration method. |
| priorityDate |
2019-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |