http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022287957-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c965b76827e500120c872ebf22a51655 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-325 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-36002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba8867d358eb5e683cbebd114dad405a |
| publicationDate | 2022-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022287957-A1 |
| titleOfInvention | Compositions and methods for using alternating electric fields to disrupt nanoparticles |
| abstract | Disclosed are methods comprising: administering a drug-loaded nanoparticle to a subject; and exposing a target site of the subject to an alternating electric field for a period of time, the alternating electric field having a frequency and field strength, and wherein the alternating electric field triggers the release of the drug from the drug-loaded nanoparticle at the target site of the subject. Disclosed are methods comprising: administering a drug-loaded nanoparticle to a subject; and exposing a target site of the subject to an alternating electric field for a period of time, the alternating electric field having a frequency and field strength, wherein the alternating electric field triggers the release of the drug from the drug-loaded nanoparticle at the target site of the subject, thereby decreasing non-target site specific release of the drug. Disclosed are methods of treating cancer in a subject comprising administering a drug-loaded nanoparticle to a subject having cancer; and exposing a target site of the subject to an alternating electric field for a period of time, the alternating electric field having a frequency and field strength, wherein the target site comprises a cancer cell; wherein the alternating electric field triggers the release of the drug from the drug-loaded nanoparticle at the target site of the subject; wherein the drug kills the cancer cell. Disclosed are methods of killing cancer cells comprising administering a drug-loaded nanoparticle to a subject; and exposing a target site of the subject to an alternating electric field for a period of time, the alternating electric field having a frequency and field strength, wherein the alternating electric field triggers the release of the drug from the drug-loaded nanoparticle at the target site of the subject, wherein the target site comprises cancer cells, wherein the drug kills the cancer cells. |
| priorityDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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