http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022283116-A1

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filingDate 2020-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c1c0590e5d16c7f68976c58afbaa1de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d63fbab1d4f8f1f76fad5458311d519e
publicationDate 2022-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022283116-A1
titleOfInvention Device for detecting analytes in a sample, and methods of use thereof
abstract Devices for detecting an analyte in a sample suspected of containing the analyte, are provided. The devices include bio-functional, nanostructured, isoporous membranes (BNIM) integrated organic electrochemical transistor (OECT), herein BNIM-OECT, for the rapid and sensitive detection of the presence of an analyte of interest, in a sample, for example, a biological sample. The membrane (i.e., BNIM) is physically separated from the OECT channel therefore the electronic device can be used multiple times. The isoporous membrane is functionalized to include a binding partner for the analyte being detected. The BNIM-OECT can be used for disease detection, by functionalizing the BNIM-OECT with a binding partner to an analyte associated with the disease, applying a collected biological sample to the BNIM-OECT. A decrease in channel current as a result of analyte binding to its binding partner on the isoporous membrane indicates the presence of the analyte in the sample.
priorityDate 2019-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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