http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022273580-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 |
| filingDate | 2020-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aed5da36b0e6462b02638cc9588bf895 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e95c32cf7dc32470bfd15c28950e028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e9fb52da29604672226b83e5e380ad4 |
| publicationDate | 2022-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022273580-A1 |
| titleOfInvention | Method for preparing drug-loaded silk fibroin nanocapsule, and product thereof |
| abstract | The present invention discloses a method for preparing a drug-loaded silk fibroin nanocapsule, and a prepared drug-loaded silk fibroin nanocapsule. The method comprises: performing a coating treatment of applying alternating layers of silk fibroin and 3-aminopropyl triethoxysilane on functionally modified polystyrene microspheres, to ultimately obtain a multi-layer-structured coated polystyrene composite with a negative or positive potential, and finally removing the functionally modified polystyrene template with a template-removing reagent, to obtain a drug-loaded silk fibroin nanocapsule. The functionally modified polystyrene microspheres are positive potential microspheres, and silk fibroin is used for the first coating. In the case of negative potential microspheres, 3-aminopropyl triethoxysilane is used for the first treatment. The process is simple and has wide applicability. The dimensions of the prepared microcapsule can be controlled at the nanometer level, so that the microcapsule can more effectively transport a drug to the interior of a cell to come into play. |
| priorityDate | 2019-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.