http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022265866-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09febdc1c309bef3e4370aac8747b89e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4391022aecf19ad30e928aaeecdc66f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec70e1bf76a45bd90b85841d21f84661 |
| publicationDate | 2022-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022265866-A1 |
| titleOfInvention | Methods for analyzing tumor innate immune interactions using the zebrafish xenograft model as a living biomarker |
| abstract | The present invention discloses methods of analyzing the immune reactive status of human tumors using zebrafish xenografts. n By analyzing the engraftment/clearance profiles in zebrafish xenografts, the present invention aims to identify new mechanisms of innate immune evasion/suppression and consequent biomarkers for immunotherapy; innate immunomodulator molecules that can be used in combination with established cancer immunotherapies, therefore engaging both arms of the immune system. n Further, the present invention allows the discovery of compounds with capacity to increase engraftment and, therefore, find immunomodulator molecules that can be used in transplantation procedures. Finally, this in vivo method will allow to select eligible patients for immunotherapy treatment. |
| priorityDate | 2021-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.