http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022265676-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f780c6fdbb463e17a8c7c0c069ac3c42
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-14
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-14
filingDate 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dc1c30242d8801031ba4546b85e0aaf
publicationDate 2022-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022265676-A1
titleOfInvention Tricyclic dibenzothiazepine type compounds for use in the therapy of cdkl5 disorder
abstract Tricyclic dibenzothiazepine compounds for use in the treatment of CDKL5 disorder. Specifically, a compound of Formula I, or a pharmaceutically or veterinarily acceptable salt thereof, or a pharmaceutically or veterinarily acceptable solvate of either entity for use in the treatment of CDKL5 disorder in a mammal, wherein a compound of Formula I comprises: n n n n n n n n n n or a pharmaceutically or veterinarily acceptable salt thereof, or a pharmaceutically or veterinarily acceptable solvate of either entity, n wherein: n R 1 and R 3 each independently represent, at each occurrence when used herein, n H or C 1 to C 5 alkyl; n R 2 represents halo; n R 4 and R 5 each independently represent H; n R 6 represents —C(O)OR 9 ; n X represents CH 2 , O or S; n R 9 represents H or C 1 to C 5 alkyl; n and, n m is an integer from 1 to 6 inclusive.
priorityDate 2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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