http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022251634-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-165 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-20 |
| filingDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0eb22c62a4e5a49f78cfc1a6cedf9196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37999b2051d3dd977302adad82e53af0 |
| publicationDate | 2022-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022251634-A1 |
| titleOfInvention | Method for recording elapsed time in dna of cells |
| abstract | The present invention relates to a method for recording the passage of time in DNA of cells. More specifically, the present invention relates to a method for measuring time which has elapsed from a predetermined time point in cells using target genome editing system, and to a system for measuring time in cells. The method of the present invention is a new synthetic biological clock that enables the accurate in vivo measurement of the time which has elapsed from a defined time point to any time point. Through the system of the present invention, time information ranging from hours to weeks can be accurately recorded in vitro or in vivo in DNA of animal cells and living animals, and the time which has elapsed from a recorded time point can be measured at an unknown time point through DNA sequencing. Also, when the synthetic DNA clock of the present invention is used, it is possible to accurately record and measure the exposure time of cultured cells to chemicals and the lifespan of living animals remaining after time starts to be recorded in the living animals. In addition, temporal information regarding various intracellular signal transductions can be recorded and decoded in DNA in the cells using the synthetic DNA clock of the present invention. |
| priorityDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.