Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f86011f07c06ae08c31c0c7d85dcf87d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52 |
filingDate |
2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f185ef7d6bf10b24743c73f52e4b9df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c31b285dbf7a721a65a60cf72a2a6ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98eeb9dcf59948fe9653c899f32145c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84d4b0a42e984e09fcb1b8c11cdace29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640ee1f9f129088385ffeb7650a438db |
publicationDate |
2022-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022251531-A1 |
titleOfInvention |
Non-toxic protease having improved productivity |
abstract |
The present invention relates to a mutated non-toxic protease in which the amino acid cysteine (Cys) at position 430 of a non-toxic protease represented by the amino acid sequence of SEQ ID NO: 1 is substituted with an amino acid other than cysteine. According to the present invention, it is possible to recover a refolded non-toxic protease from an insoluble fraction from which the non-toxic protease was almost impossible to recover in the prior art, and thus it is possible to produce the non-toxic protease with significantly improved productivity. |
priorityDate |
2019-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |