| abstract |
Compositions consist essentially of trigonelline or consist of trigonelline. The compositions can be used in food or beverage applications, pharmaceutical formulations, or as a dietary supplement. The compositions can be administered to a mammal to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (“NAD+”) in cells and tissues for improving cell and tissue survival or overall cell and tissue health. Preferably, NAD+ biosynthesis is increased in one or more cells of a mammal, for example one or more cells that are part of at least one body part selected from the group consisting of a liver, a kidney, a brain, and a skeletal muscle. |