http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022242892-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5054 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-50 |
| filingDate | 2020-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9da2053ba5c3fd23976371602bfb18f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a1e650edf08e68941f5ea0cf4aa9021 |
| publicationDate | 2022-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022242892-A1 |
| titleOfInvention | 1,2-bis(diphenylphosphinoalkylamido)-1,2-disubstituted ethane, and its synthesis and application |
| abstract | The present invention relates to the design and synthesis of a class of novel chiral phosphine ligand, 1,2-bis(diphenylphosphinoalkylamido)-1,2-disubstituted ethane, and use in asymmetric catalytic reactions, such as asymmetric catalytic synthesis of pyrazoline-5-one with a chiral quaternary carbon center, i.e., highly enantioselective synthesis of 3-methyl-4-benzyl-4-(2-butyl-2,3-butadienyl)pyrazoline-5-one by using 3-methyl-4-benzylpyrazoline-5-one and benzyl (2-butyl-2,3-butadienyl) carbonate with tris(dibenzylideneacetone)dipalladium-chloroform adduct and this novel ligand as catalysts. The ligand designed by this present invention has the following advantages: the structure is novel, the synthesis and enlarge are simple, the enantioselective control effect in the practical reaction is excellent, which has a broad application prospect in chiral catalysis. |
| priorityDate | 2019-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.