| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5498907541060cb9244b2292e98f256
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_643e9a9bb3fbe08f35d2093bd1094b1d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7028 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2020-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7171e1e5baf508e11ed240d6013ac54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_362ca51bde3c0549cad101eaf5a276ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f01c1047929445b8fd8ab0216ba013c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b0e9e068d2feaa74f984203697ae0c0 |
| publicationDate |
2022-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022233558-A1 |
| titleOfInvention |
Method and composition for predicting efficacy of bcl2/bcl-xl inhibitors on cancer |
| abstract |
Provided are biomarkers for predicting the efficacy of BCL-2/BCL-XL dual or selective inhibitors in treating cancer patients. The biomarkers comprise a complex comprising BCL-2 or BCL-XL. Also provided are methods and compositions, e.g., kits, for evaluating levels of the biomarkers and methods of using such levels to predict a cancer patient's response to the BCL-2/BCL-XL dual inhibitors or BCL-XL or BCL-2 inhibitors. Such information can be used in determining prognosis and treatment options for cancer patients. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11554127-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021361678-A1 |
| priorityDate |
2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |