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filingDate 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d3936c9de0e7e7dba990d224b2e1a13
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publicationDate 2022-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022228217-A1
titleOfInvention Epiaging ; novel ecosystem for managing healthy aging
abstract The present invention relates to method for calculating biological age of a subject and across multiple subjects by performing polygenic DNA methylation on biomarkers which comprise measuring the methylation status of 13 CG sites positioned in a putative antisense region to ElovL2 gene, ElovL2 AS1 region. Further, the present invention provides a computer-implemented method for providing recommendations for lifestyle changes in form of a self-learning “ecosystem” for lifestyle management of biological aging using a novel measurement of the DNA methylation clock as a continuous dynamic outcome. The present invention also relates to combination of DNA methylation biomarkers for calculating biological age, a kit for determining the biological age. Further, the present invention discloses the use of the disclosed methods for calculating biological age in a method of assessing the effect of the effect of a biological intervention and in a method of screening for an anti-ageing agent.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11687536-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022114184-A1
priorityDate 2019-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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